Borrelia Burgdorferi and Lyme Disease

Borrelia Burgdorferi and Lyme Disease Megan Eifert   Background The helical shaped pathogen Borrelia burgdorferi is a member of spirochete bacterium that is best known as the causative agent of Lyme disease. Belonging to the phylum Spirochaetes, these bacteria are characterized by a lipid bilayer known as the outer membrane sheath, as well as an inner space between a long cylindrical protoplasm and outer membrane sheath referred to as the periplasm (Metapathogen, 2012). Genus Borrelia comes from the French bacteriologist Amedee Borrel who identified a set of organisms that caused tick-borne and louse-borne relapsing fever in humans and animals (Metapathogen, 2012). Specific to the group Borrelia burgdorferi typically only 1 ÃŽÂ ¼m wide but up to 25 ÃŽÂ ¼m long, a unique characteristic of wavelike bodies and flagella are bound between the inner and other cell membranes, proving to be vital in the success of these bacteria. This feature is especially important to defining the highly invasive classification of these bacteria by allowing the pa thogen to travel effectively through tissue of its infected host (Burke, 2005). Similarly an important feature of B. burgdorferi are their outer surface proteins that have been researched to play a large role in the transmission of the pathogen as well as been the focus of those working on producing an effective vaccine against it (Burke, 2005). Metabolic capabilities are limited in these bacteria and therefore gaining energy is a task relied upon the hosts in which B. burgdorferi infect. With an optimal growth condition at 32 ° C in a low oxygen environment, even the best conditions demonstrate a slow generation time of between 12 to 24 hours (Tilly, 2008). Using glucose and carbohydrates as their main energy source, their genome has been identified to encode transport proteins such as ABC transporters and enzymes that are utilized in the phosphotransferase system and others similar that have the ability to gather compounds from both host or environment (Burke, 2005). Without the capability to produce energy from the TCA cycle, oxidative phosphorylation or an electron transport train, B. burgdorferi utilizes substrate-level phosphorylation to produce ATP within the cell necessary for these bacteria to remain successful (Rosa, 2005). There are three species of B. burgdorferi that have been identified in causing most cases of human disease. With a natural reservoir found to be a variety of small mammals, B. burgdorferi sensu stricto, B. garinii, and B. afzelii are the typical strains identified in almost all cases of clinical disease. Specific to the United States, B. burgdorferi sensu stricto is the only species clinically associated with human disease whereas all three species have been found in Europe, and B. garinii and B. afzelii have both been identified in Asia (Metapathogen, 2012). Clinical Significance Although infection within natural hosts does not regularly cause disease, Borrelia burgdorferi is a tick-borne obligate pathogen that when infection occurs in humans can elicit the human immune-patholgical response and cause Lyme disease (Borrelia, 2007). Dr. Alan Steere and his team first clinically identified Lyme disease in 1977 as an infectious illness that continues to be the leading vector-borne disease in the United States (Borrelia, 2007). Through research of geographic regions with a surge of patients exhibiting seasonal occurrence of similar symptoms, Dr. Steere hypothesized the epidemiology of Lyme disease suggested transmission of the pathogen was occurring through an arthropod vector. Following the lead of Dr. Steere, a Dr. Willy Burgdorfer began to study a group of spirochetes found and collected from midgut tissues of ticks native to areas relative to the Lyme disease outbreaks. The bacteria isolated continuously produced a skin rash similar to erythema migrans when te sted on rabbits within a laboratory setting and samples from Lyme disease patients reacted with the bacteria when used in indirect immunofluorescence assays (WI, 2011). As a consequence of these observations, this set of organisms was first given their now recognizable name, Borrelia burgdorferi. Clinical manifestations of Lyme disease vary upon the species identified as the causative agent however; many common symptoms and features are shared across all cases of disease. According to reports from Mayo Clinic, most often the first symptoms described include an erythema migrans rash often in the shape of a bulls-eye at the site of the bite, accompanied by symptoms that most resemble an influenza-like infection (Lyme, 2015). Once patients exhibit these skin lesions, non-specific symptoms such as headaches, generalized lymphadenopathy, generalized lymphadenopathy and splenomegaly, migratory musculoskeletal pain, hepatitis, sore throat, non-productive cough, conjunctivitis or periorbital edema may arise, causing in most cases the discomfort associated with a diagnosis of Lyme disease (Lyme, 2015). Specific to most cases identified in the United States by the B. burgdorferi, arthritis is one of the main associated symptoms that patients struggle with. When infection persists to stage 2 after a few weeks, Mayo Clinic sources indicate about 15% of patients develop neurological deficits and abnormalities such as meningitis, encephalitis, cranial neuritis (including bilateral facial palsy), motor or sensory radiculoneuritis, mononeuritis multiplex, or myelitis (Lyme, 2015). Once neurological problems begin, patients can develop cardiac complications as well while continuing to experience a high amount of musculoskeletal pains throughout the body. When symptoms of Lyme disease persist beyond the typical treatment time, chronic Lyme disease can set in and patients experience post-treatment Lyme disease syndrome resulting from weakened immunity, systemic bacterial infection and inhibited cellular function and protection (Transmission, 2015). Over two-thirds of patients diagnosed with Lyme disease by infection of B. burgdorferi will develop chronic neurologic or skin involvement and non-specific arthritis. Symptoms characteristic of chron ic fatigue syndrome have been described as lasting for years following infection, proving infection with this bacterium can live in harmony within its human host making it a successful pathogen. According to the CDC, Lyme disease affects approximately 60,000 people worldwide per year however; mortality caused by the pathogen remains low at only 114 deaths reported from the disease in the United States between 1999-2003 (Transmission, 2015). Lyme disease can be accompanied by a wide variety of systemic involvement with varying clinical manifestations dependent on the stage of disease identified making both the course of illness and treatment inconsistent between patients. Borrelia burgdorferi elicits a variety of strategies in order to penetrate the immune systems of its hosts in hopes to successfully remain a viable bacterium. Inducing both the innate and adaptive immune responses, the bacteria have adapted to their reservoir hosts causing ineffectiveness of immunity to clear the bacteria out of the system entirely. Prior to activation, cleaved complement molecules form on the surface of the bacteria to help promote bacteriolysis while negatively regulating the complement system through various regulators to avoid host tissue damage (Tilly, 2008). With the goal of inhibiting the complement system, B. burgdorferi utilize outer surface proteins hosted on their outer membranes to bind complement regulators in order to successfully inhibit the complement system and its killing response. With the complement system inhibited, the bacteria are able to better survive within the blood stream and thus promoting further disease manifestations (Tilly, 2008). Vaccination for Lyme disease is a concept of both the publics past and future but not present. Administered in three doses, the first and only of its kind a vaccine against Lyme disease was licensed in 1998 by SmithKline Beecham (Poland, 2011). The vaccine in theory was to stimulate antibodies that would attack B. burgdorferi within the vectors gut as it fed on its human host, thus preventing the bacteria to enter the body and showed to be 78% effective following all doses completion (Poland, 2011). In 2002 the company producing the vaccine had removed it from the market and ever since a similar vaccine to protect humans against Lyme disease has not been re-introduced to the public. Diagnostic and Treatment Diagnosis of Lyme disease can be difficult due to the various nonspecific signs and symptoms associated with not only infection by Borrelia burgdorferi, but characteristic of many similar diseases. Typically the rash characteristic of Lyme disease in an area known to host ticks that transmit the disease does not warrant further testing for a diagnosis. Most often used to provide a more definitive Lyme disease diagnosis is the use of an enzyme-linked immunosorbent assay test. ELISA detects Lyme disease by identifying antibodies to its causative pathogen, although this test may provide false-positives or negatives even when the bacteria is present due to the stage the disease is in (Borrelia, 2007). If an ELISA test proves positive, Western blot tests are used to confirm infection of B. burgdorferi, which identify antibodies against multiple proteins characteristic of the pathogen (Lyme, 2015). Several therapeutics are used to treat patients infected with Lyme disease and as with most disease treatments the sooner treatment is able to begin, the better and sooner recovery is achievable. Oral antibiotics are used as the first line of standard treatment with an early-stage diagnosis of Lyme disease. With a 14 to 21 day regimen, antibiotics prescribed according to Mayo Clinic typically include doxycycline for adults and children older than 8, or amoxicillin or cefuroxime for adults, younger children, and pregnant or breast-feeding women (Lyme, 2015). Oral antibiotics are used most often to treat skin rashes and influenza-like symptoms associated with the first stages of Lyme disease. Intravenous antibiotics may be employed for treatment if the disease has involved the central nervous system and this method of treatment has been shown to be effective in eliminating the infection but not without lingering symptoms according to the CDC. When chronic Lyme disease or post treatment Lyme disease syndrome is suspected, antibiotics are not effective in treating symptoms or the disease, and effective treatments remain unknown once the disease has progressed on. Although much research is unavailable, many living with chronic Lyme disease explain turning to natural remedies as treatment such as dietary suggestions to help increase immune function or adding supplements to help improve cell structure and function to help alleviate symptoms (Borrelia, 2007). References Borrelia burgdorferi. (2007). Retrieved March 25, 2017, from http://www.lymeneteurope.org/info/borrelia-burgdorferi Burke G, Wikel SK, Spielman A, Telford SR, McKay K, Krause PJ, et al. Hypersensitivity to Ticks and Lyme Disease Risk. Emerging Infectious Disease. 2005 Jan. Volume 11(1), p. 36-41. Lyme disease. (2015). Retrieved March 25, 2017, from http://www.mayoclinic.org/diseases-conditions/lyme- disease/basics/definition/CON-20019701 MetaPathogen.com/Borrelia burgdorferi. (2012). Retrieved March 25, 2017, from http://www.metapathogen.com/borrelia/ Poland GA. Vaccines against Lyme Disease: what happened and what lessons can we learn? Clin Infect Dis. (2011) 52 (suppl 3): s253-s258. Retrieved March 25,2017. Rosa, PA., Tilly, K., and Steward, PE. The Burgeoning Molecular Genetics of the Lyme Disease Spirochaete. Nature Reviews Microbiology. 2005. Volume 3(2), p. 129- 143. Tilly, K., Rosa, P. A., Stewart, P. E. (2008, June). Biology of Infection with Borrelia burgdorferi. Retrieved March 25, 2017, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440571/ Transmission. (2015, March 04). Retrieved March 25, 2017, from https://www.cdc.gov/lyme/transmission/ WI, K. T. (2011, May). Lyme Disease. Retrieved March 25, 2017, from http://textbookofbacteriology.net/Lyme.html

Advantages Of Social Media

Advantages Of Social Media Connections. You are friends with people who have other friends, and so on. By using a social networking site, you can do what you can and get connected with these people to form a web of connections that can give you leverage if you play your cards right. Breadth of Knowledge -connectedness that students can experience through social media use. It is now easier than ever to know (or find out) something about almost anything in the world through connected media. Additionally, students can be connected to a broader base of opinions and world views through instantaneous global connections. Technological Literacy All social media relies on advanced information and communication technologies that seamlessly work to build and support technological literacy.. Worldwide Connectivity, No matter if you are searching for that former college roommate, your first grade teacher, or an international friend, there is no easier or faster way to make a connection than via the social network. Although Facebook, Twitter, LinkedIn and MySpace are probably the most well known social networking communities, there are new websites popping up regularly that are dedicated to allowing people to connect and to interact via the Internet. These connections can help one with a variety of things such as: Finding romance, Seeking a new job, Locating assistance, Getting and giving product and service referrals, Receiving support from like-minded individuals, Making or receiving advice on career or personal issues. In many ways, social communities are the virtual equivalent of meeting at the general store or at church socials to exchange news and get updated on friends and families.. Commonality of Interest, When you opt to participate in a social network community, you can pick and choose those individuals whose likes and dislikes are similar to yours and build your network around those commonalities.You can meet with your friends anytime you have an Internet connection and whenever you find them online. Real-Time Information Sharing, Many social networking sites incorporate an instant messaging feature, which means you can exchange information in real-time via a chat. This is a great feature for teachers to use to facilitate classroom discussions.In addition, the Internet is the ultimate online textbook. Students no longer need to take out six library books at a time. Much of what they need to know they can find online. Free Advertising, Whether you are non-profit organization who needs to get the word out about your upcoming fundraiser or a business owner marketing a new product or service, theres no better way to get your message in front of millions of people 24/7. The best part is it that you can spread the word through social networking profiles for free. Increased News Cycle Speed, Social networking has revolutionized the speed of the news cycle. Many news organizations now partner with social networking sites like Twitter, YouTube, and Facebook in order to both collect and share information. One can get a sense of what is going on in the world just by watching trending topics from many of these sites. This has led to the development of a near instantaneous news cycle as millions of social networking updates rapidly spread news and information. Social media has the power to drive traffic to your website, blog, articles, etc. Social media is able to bring people together, especially when promoting global products or cause-related campaigns and ideas since it allows people from the different geographical location to meet at a single point and express their views. Social media could be the spark you are looking for to attract attention to your site, product or service. It could also be used to further build loyalty and long-term relations with your audience. Social media marketing could always be a fun and creative method of doing business. Facilitates open communication, leading to enhanced information discovery and delivery. Allows everyone to discuss ideas, post news, ask questions and share links. Targets a wide audience, making it a useful and effective recruitment tool. Disadvantages of Social Media: Distraction -talking not about the momentary distraction of an isolated text message, but rather the way in which social media involvement provides an acceptable diversion from intellectual pursuits. Essentially, he is arguing that it is socially safer to stay connected to peers through always-on social media, than it is to put oneself out there by having a legitimate opinion about a serious topic and disconnecting from the social networks long enough to put it out there. Pressure to Conform examples of students confiding in him that one of the main reasons behind their 24/7 connection is a fear of not keeping up with peers or appearing like a loser in public, as one of his students confided in a class journal. Risk Aversion unclear about whether students aversion to taking risks is a symptom of social media use or is directly caused by it, but the point is no less important either way. Social media engagement supports a culture of avoidance which operates in direct opposition to the idea that students need to take risks and fail in their academic endeavors in order to become successful innovators. Shallowness . Twitter, text messages, and other social media tools focus on brief, quick, shallow interactions that do not encourage either deep social engagement or intellectual exploration. There is, after all, only so much information that can be obtained in 140 characters. when you make a mistake offline, a few will know but when you make a mistake in front of hundreds or thousands of you online audience, most of them will know Face to Face Connections are Endangered, A huge advantage of these social communities has a reverse side effect that is also a big disadvantage of social networking: they reduce or eliminate face-to-face socialization. Because of the autonomy afforded by the virtual world, individuals are free to create a fantasy persona and can pretend to be someone else.It is hard to say no, be rude, or ignore someone when you are looking them in the eye. Its incredibly easy and quick to unfriend or unfollow someone or simply block their efforts to make a connection. Just one click of the mouse and your problems are over. Tweens and teens are at higher risk because those years are when they are learning to interact with others or build and maintain relationships. A report from the National School Boards Association shows that of the children in these age groups that use a social network, 41 percent spend their time posting messages. They are not spending this time in face-to-face interactions with their peers or others nor are they developing the necessary social skills for future success. Cyberbullying and Crimes Against Children, Use of social networks can expose individuals to harassment or inappropriate contact from others. Unless parents are diligent to filter the Internet content to which their families are exposed, children could be exposed to pornography or other inappropriate content.. Risks of Fraud or Identity Theft, Whether you like it or not, the information you post on the Internet is available to almost anyone who is clever enough to access it. Most thieves need just a few vital pieces of personal information to make your life a nightmare and if they successfully steal your identity, it could cost you dearly. Time Waster, A Nielsen report explains that social networking can be a big waste of time that sucks 17 percent of our Internet time down the non-productivity drain. it is also true that it is easy to become distracted and end up spending valuable time on games, chats or other non-related activities. Corporate Invasion of Privacy, Social networking invites major corporations to invade your privacy and sell your personal information. Facebook projects it will earn $3.8 billion in revenue in 2011. Thats not bad for a free site. If Facebook and other social networking sites dont charge their members, however, how do they make so much money? They do it by selling the ability to specifically target advertisements. On social networking sites, the website isnt the product, its users are. These sites run algorithms that search for keywords, web browsing habits, and other data stored on your computer or social networking profile and provide you with advertisements targeted specifically to you. At the same time, you may be giving the site permission to share your information with outside sources unless you specifically generate settings that disallow them to do so. Participating in applications like Farmville may also be allowing outside vendors access to your private information. In order to get social medias full effect, you need to understand how it works, when and how to use it and which channels to focus on depending on your end goal of using social media. Social media can have a negative influence on students and workers productivity. Employees may waste valuable time using social media channels such as Facebook and Twitter. They can also use social media to attack the companys reputation! When social media is used excessively or in the wrong way, it could have serious detrimental outcomes on both mental and even physical health of individuals. Opens up the possibility for hackers to commit fraud and launch spam and virus attacks. Increases the risk of people falling prey to online scams that seem genuine, resulting in data or identity theft. May result in negative comments from others about everything we put in our social media example our video in youtube Potentially results in lost productivity, especially if students are busy updating profiles, etc. Lack of Anonymity,You are putting out information about your name, location, age, gender, and many other types of information that you may not want to let others know. Most people would say be careful. As long as people can know who you exactly are, then some can find ways to do you in. Scams and Harassment, While many sites apply certain measures to keep any of these cases of harassment, cyber-stalking, online scams, and identity theft to an absolute minimum, you still may never know. Time Consuming, that it would just be a waste of time for you. The key to social networking is that it is supposed to be fun, whether you are just doing it for kicks or clicking around for study purposes. That should be reasonable enough for anyone, but there are those people who dont see the point. For them, it can be a disadvantage.

Segregation and Civil Rights Essay -- Black Civil Rights in America

The definition of the term â€Å"American character†, in general, was in fact plagued during the 1950s. Instead of the believable â€Å"picture perfect† definition that American character was portrayed to be, it was really constructed of major struggles between different races. In particular, the significant struggles between blacks and whites. The 1950s was a crucial decade of change for African Americans. The results of the battle for nine African American children to attend Central High School (Little Rock, Arkansas) in 1957 promoted social advance for the permanent desegregation of public school systems. However, even with this nationally recognized social advance, the concept of â€Å"American character† varied between blacks and whites due to racial and social inequality. Back in 1896, the United States Supreme Court ruled in Plessy v. Ferguson that racial discrimination was constitutional. This decision gave the states permission to segregate citizens by race and to operate â€Å"separate but equal† facilities all around. Terrence Roberts, in his novel Lessons from Little Rock, shares his first-hand experience of neglect from society. Roberts states, â€Å"As a black person, I had no legal right to assume that I could participate fully in civic, educational, economic, political, or social affairs† (Roberts 19). Whites lived in great satisfactory after this decision. They remained the group with the upmost authority and continued to mistreat blacks at any cost, including denying them the right to an equal quality of education. Their definition of American character, being the wealthiest and the smartest, was still acknowledged as the existence of African Americans became more and more surreal. In 1954, the Supreme Court ruled in Brown v. Boa... ... Kirp, David L. Political Science and Politics, Retreat into Legalism: The Little Rock School Desegregation Case in Historic Perspective Vol. 30, No. 3 (Sep., 1997), pp. 443-447 Published by: American Political Science Association. (http://www.jstor.org/stable/420120) Lawson, Steven F. and Payne, Charles. ""Mob Rule Cannot Be Allowed to Override the Decisions of Our Courts": President Dwight D. Eisenhower’s 1957 Address on Little Rock, Arkansas." History Matters: The U.S. Survey Course on the Web. Lanham, Maryland: Rowan & Littlefield Publishers, Inc., 1998. Web. . Reumann, Miriam G. American Sexual Character: Sex, Gender, and National Identity in the Kinsey Reports. Berkeley and Los Angeles: University of California Press, 2005. Roberts, Terrence J. Lessons from Little Rock. Little Rock, AR: Butler Center, 2009. Print

Much Ado About Nothing Essay -- essays research papers

William Shakespeare's Much Ado About Nothing is a play involving by deception, disloyalty, trickery, eavesdropping, and hearsay. The play contains numerous examples of schemes that are used to manipulate the thoughts of other characters; it is the major theme that resonates throughout the play. Ironically, it is one of these themes that bring serenity to the chaos that encompasses most of the play. The first example of deception we see is with the characters of Beatrice and Benedick. These two characters provide the humor throughout Shakespeare's comedy; their repartees and soliloquies tend to leave the reader smiling and anxious for more dialogue between them. Beatrice and Benedick have had a relationship prior to their battles of wit to which she alludes to in Act 2: "Marry, once before he won it for me with false dice; / Therefore your grace may well say I have lost it’ (2.1.265-7). We see that at one time in the past they had a relationship that somewhere went wrong. The deception of Beatrice and Benedick comes courtesy of Don Pedro in Act 2. In this scene, Don Pedro, out of pure amusement, asks Leonato, the governor of Messina, and Claudio, a lord attending on Don Pedro, for help to bring these two together: "If we can do this, Cupid is no / longer an archer; his glory shall be ours†¦" (2.1.363-4). In Act 2.3, Claudio, Pedro, and Leonato, see Benedick in the garden and decide that that is the right moment for them to try and trick Be...

The Agricultural Revolution Essay -- Essays Papers

The Agricultural Revolution The agricultural revolution of the nineteenth century was caused by many important factors. Before the revolution, people working in the farms were living entirely on what they could produce. Most farmers were extremely hesitant to make any changes in the methods they had been using for farming mainly because, although the payoff would be fairly large, if it didn't work, the mistakes could cost them their lives (Kagen). Farmers in the nineteenth century had several problems to deal with. One of the biggest problems was the fact that they were subject to the whims of nature. If there was a particularly bad storm, the crops for the year could be lost. If this happened, the family would be left with whatever food they had stored. Unfortunately, there was usually very little food left in storage, since they were required to pay taxes on the land they worked, and that was usually paid in grain. There was usually no extra food, other than what they stored for the win...

Jose Rizal’s Life Essay

1. Surname-â€Å"Rizal† Jose Rizal and his family got the surname ‘Rizal’ from his Chinese ancestor Domingo Lameo. Rizal means â€Å"Ricial or grains†, and they started using it 1731. His true surname is Mercado, but to keep his family safe he used the surname Rizal. His brother insisted that he adopt the name Rizal in order to avoid the obvious stigma that the Alonzo y Mercado name had recieved from Paciano’s association with Father Burgos, and the family’s prominence in the native community. Read more: http://wiki.answers.com/Q/Where_did_Jose_Rizal_get_his_surname_Rizal#ixzz1C3si8ka5 http://www.schillerinstitute.org/educ/hist/rizal.html 2. Jose Rizal’s reason in going out of the country Rizal went out of the country because he wants to discover,explore other places and to learn new things. Rizal went to other countries to study, he also wants to learn different languages, he studied medicine because he wants to give cure of his mother’s eyes. Rizal build up businesses, experiencing life to the fullest while he’s out of the country, he changes his girlfriend whenever he wants. But going out of the country is not about pleasure, Rizal was there to hide, because he’s life was already in danger that he has to hide for awhile. There are many accussations thrown on him during those times. He has to go out of the country with all his love for his family and for all the filipinos; to protect his family and his countrymen. If he choses to expose himself to the opponent, whole filipinos life will be in much danger than it really was. 3. Part of Rizal’s life  2 May 1883 – Visitacià ³n 8 – 3rd floor, No. 4 Yesterday, one year ago I left my home to come to this country. How many illusions one entertained and how many deceptions! Yesterday, all day and night, I kept recalling all that had happened to me since then. I took my diary and read it, which reminded me of faded impressions. Though sick, I’ll continue my diary because I see that it is most useful and above all it consoles the soul when nothing more remains of its former treasures. This morning I went to see the celebration of Dos de Mayo (2nd May) [05]. There were many people around the obelisk where I saw a tiny altar with some candles. Everywhere could be heard the cries of newspaper vendors which recalled the 2nd of May. In the afternoon we — Zamora, Villanueva, and I — went to see the civic procession. Many soldiers and members of the different corporations. The King does not attend this national celebration. I received from the Philippines a letter of L.R. [06] of 26 March. * Rizal went out of the country because of his true love for the country and his family. He wants to protect those people that he really love. During the day that he wrote it, he’s sick, he’s like crying everything to his diary and that is the best that he did, to write, he write everything coz he knows that those writings will be very useful to help and save his country, but what i like about it is that he uses a diary in dealing with his emotions, the diary is like someone who will collect every details of your story. It’s almost a treasure, it holds everything even secrets. During that sad moment, rizal recalls some moments of his life, from the day that he’s in the Philippines up to the day that he has to leave for the sake of everyone. With a diary, everything was just like yesterday. I was really touched will this part of his diary. Even he’s sick he still keeps on writing, i can really realate here, i can imagine him writing while recalling those sad moments of his life, it’s painful and really wanna makes me cry, because Rizal has been a very good man ever since he was born, Rizal was full of love, he’s really humble, and being humble is not an easy thing to learn. It’s not just about doing good things, it’s about doing good things from the heart, and Rizal was always sincere on what he intended to do same with what he really does..even sacrificing his own life, from his heart he sincerely wants to give it up just to save every life of his country men. And that intention will never be easy to do, you will just learn to do it when you’re humble and full of love just like Rizal, his intentions are good and it really reflects him . Life of rizal was not that good at all, he has to sacrifice, he has to suffer, he has to hide even tough all that he want was to write and make the filipinos realize that they’re being cheated and abused by those foreigner, those people who came from other country was very deceitful, they’ve been a dictator and pretentous that the filipinos are not awared of it and they let their fears and stupidity control them. He died beacuse of his love for every filipino and it’s not right to question him being our national hero, after all that he has done, Rizal’s diaries has been very useful, all of his writings are useful, it really tells how he fought for our country in more simple ways. Every writings has a story to tell. I like every part of Rizal’s life when he’s writing, i don’t know all that he write but i like that he is writing. It’s not just about the diary, i mean everytime that he write. Coz i want to write as well as if i’m a writer but i don’t know where to start coz i think you really have to be knowledgeable, it’s not just you’ll write but you have to make sure that it has an appeal and it will effectively influence the readers, so i am really amazed because Rizal was very smart and god has given him that talent to write, he’s full of passion on everything. Before and now, he is a very good author of those well known books. He has influence everyone before to fight with him for the country against those user and abusive people from other country.

Agro Based Industries

Agro-based industry would mean any activity involved in cultivation, under controlled conditions of agricultural and horticultural crops, including floriculture and cultivation of vegetables and post-harvest operation on all fruits and vegetables. The development of agro-industries has assumed crucial importance in the economic planning and progress of the country. There are extreme variations among different states in the number of processed food industries.It is also evident from this study that except potatoes, all the other perishable products have been showing inadequate number of cold storage plants and low capacity utilization of the existing units. This study suggests that there is a need to develop the processed food industries throughout the country in order to provide more employment opportunities and to reduce the regional imbalances.The main focus of Agro based industries is: Livestock farming – Livestock are domesticated animals raised in an agricultural setting to produce commodities such as food, fiber and labor. Crops- Cultivation of crops. Aquaculture – The cultivation of aquatic animals or plants for food. Livestock farming is a type of farming with living animals.Livestock farming consists of Poultry farming where birds are grown for eggs and its meat, Dairy farming where milk giving cattle are grown for dairy products, apiculture where bees are grown for its honey, and cattle farming where cattle is grown for meat. Aquaculture can also be considered as a type of livestock farming dealing with water-living animals and plants. Crops, as you know are useful plants that are needed by humans. Crops consist of Food crops, beverage crops, fiber crops and fodder crops. Food crops are crops that grow food.